Light as well as wound healing

I just recently came across a extremely fascinating journal called “Recent Patents on Biomedical Engineering” to keep me as much as date with recent advancement in this field as well as checked out a extremely fascinating article on a new gadget which I would like to show the visitors of this blog.

This has nothing to do with training as well as athletic performance, however, thinking about that in get in touch with sports unfortunately athletes do get injured as well as may experience from wounds, I believed this might be something of rate of interest for may of the readers.

The gadget in concern is utilized to perform a type of therapy called Phototherapy. Phototherapy, the utilize of light for healing, has in recent years been a field of advanced multidisciplinary research. This modality has been shown to be helpful in a wide as well as diverse array of maladies including the healing of chronic as well as acute wounds, as demonstrated in the utilize of laser light as well as LED (Light Emitting Diode) technology. many in-vitro studies as well as animal designs have shown the appealing impacts of phototherapy on wound healing. Human studies with laser light have demonstrated higher amounts of epithelialization for wound closure as well as stimulation of skin graft healing (Conlan MJ, Rapley JW, Cobb CM. Biostimulation of wound healing by low-energy laser irradiation. J Clin Periodont 1996; 23: 492-496; Whelan HT, Smits RL Jr, Buchman EV, et al. impact of NASA light-emitting diode irradiation on wound healing. Clin Laser Med Surg 2001; 9: 105-14).

Visible as well as near IR light can be absorbed by cellular photosensitizers such as cytochromes as well as flavins/riboflavins . Absorption of light by these photosensitizers triggers their excitation as well as relaxation by transferring electrons to O2, thereby generating reactive oxygen types (ROS). ROS are most likely finest understood in biology for their capability to cause oxidative stress. They can damage DNA, cell membranes as well as cellular proteins as well as may lead to cell death. However, low ROS fluxes play an important function in the activation as well as manage of many cellular processes, such as the release of transcription factors, gene expression, muscle mass contraction as well as cell growth (Rhee SG. Redox signaling: hydrogen peroxide as intracellular messenger. Exp Mol Med 1999; 31: 53-59). Therefore, it makes sense that an appropriate does of phototherapy might be helpful for wound healing (and I would like likewise to add…if specific light wavelengths can be reach deep sufficient muscle mass healing?).

Various gadgets have been implemented in phototherapy, particularly in wound healing. the most prevalent to date are low level lasers (~10mW/cm^2) as well as LEDs which normally create low energy intensities (10-50 mW/cm^2) at a band width of around 10 nm. Broadband light emitting systems with visible-range as well as near IR only were neglected up until just recently because of the prospective of broadband stimulators (400-800nm) to determine photobiostimulation.

In the paper provided by Lubart et al. (2008)  a new gadget including a halogen lamp with appropriate filters for the UV as well as IR wavelengths, as well as emitting light only in the visible as well as near IR region, 400-800 nm was tested on diabetic patients as well as patients with chronic ulcers.The authors specify that the capability to irradiate big areas is extremely important for wound-healing as well as for killing bacteria, in contradistinction to the narrow laser or LED beam. one more advantage is its low cost, which will allow patients to purchase it for house use.

The results are rather impressive (images from recent Patents on Biomedical engineering 2008, 1, 13-17):

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Also, this light configuration was capable of sensibly capable of eradicating bacteria on the wound.

Interesting field, I definitively requirement to checked out more about this as I am sure there are new methods to speed up tissue repair work which may benefit athletes!

Technorati Tags: science,technology,wound healing

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